The Effectiveness Test Of Moringa Leaf Extract (Moringa oleifera) As Antifungal Against Candida albicans Growth (Literature Review)

Siti Raudah; Khoirul Anam; Muhammad Iqbal

doi:10.35728/jutelmo.v5i1.1859

Authors

Siti Raudah ITKES Wiyata Husada Samarinda
Khoirul Anam ITKES Wiyata Husada Samarinda
Muhammad Iqbal ITKES Wiyata Husada Samarinda

DOI:

https://doi.org/10.35728/jutelmo.v5i1.1859

Keywords:

Moringa leaf extract (Moringa oleifera), Candida albicans

Abstract

Moringa leaf extract (Moringa Oleifera) contains essential oils, and the main compounds that can be used as antifungals include flavonoids, alkaloids, phenols, proteins, sapanoids, tannins and terpenoids. In this literature review, the fungus used is Candida albicans with the type of extraction solvent, such as ethanol with various concentrations. Purpose: To determine the effectiveness of Moringa leaf extract in ethanol solvents with various concentrations in inhibiting the growth of Candida albicans. Method: Search literature reviews with research topics to answer existing issues or problem. The year of publication was between 2010 and 2021. The search started from January 14, 2021, to March 17, 2021, through an electronic search based on the Garuda Portal, Google Scholar, Google Search, and PubMed. Result and Discussion: 7 journals or articles obtained. Two journals showed an inhibition zone that occurred from Moringa leaf extract on Candida albicans growth with 90% ethanol solvent producing an inhibition zone of 3.0 mm and 95% ethanol solvent producing the highest inhibition zone of 14 mm, wich showed the effectiviness of Moringa leaf extract (Moringa Oleifera) on the growth of Candida albicans. In comparison, the other five journals did not show any inhibition zones formed, which showed no effect of Moringa Oleifera leaves on the growth of Candida albicans. Conclusion: Moringa leaf extract with 90-95% ethanol solvent show inhibition against Candida albicans

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Author Biographies

Khoirul Anam, ITKES Wiyata Husada Samarinda

Prodi Sarjana Terapan Teknologi Laboratorium Medis

Muhammad Iqbal, ITKES Wiyata Husada Samarinda

Prodi D-III Analis Kesehatan

References

Ayunani Dinda Fitri. 2020. Uji Efektifitas Ekstrak Daun Kelor (Moringa Oleifera) Terhadap Pertumbuhan Jamur Candida Albcan. Program Studi Analis Kesehatan. STIKes Cendikia Medika. Jombang.

Böttcher, B, dkk. 2016. Candida species rewired hyphae developmental programs for chlamydospore formation. Frontiers in Microbiology, 7:.1-17.

Campbell, C. K. dan Johnson, E. M. 2013. Identification of pathogenic fungi. John Wiley dan Sons.

Dewantari, D. A. Y. 2017. Efek Anti Jamur Air Rendaman Daun Kelor (Moringa oleifera) Terhadap Pertumbuhan Jamur Trichophyton mentagrophytes Secara In Vitro, Nomor 1: 23-30.

Fitriana Y. A.N, Fatimah N V. A, dan Fitri S.A,. 2019 Aktivitas Anti Bakteri Daun Sirih: Uji Ekstrak KHM (Kadar Hambat Minumum) dan KBM (Kadar Bakterisidal Minimum). Sainsteks, 16 (2): 101-108.

Dwi Kurniawan. 2015. Uji Aktivitas Antijamur Ekstrak Etanol

Daun Kelor (Moringa oleifera Lamk.) Terhadap Candida albicans Secara In Vitro. Fakultas Kedokteran. Universitas Tanjung Pura Pontianak. Pontianak.

Gusti Ayu Puspita Devi. 2014. “Efektifitas Ekstrak Etanol Daun Kelor (morenga olifera) Sebagai Antifungal Terhadap Candida Albicans Secara InVitro”. Fakultas Kedokteran. Universitas Brawijaya. Malang

Isitua, C. C. Ibeh, I. N, dan Olayinka, J. N. 2016. In Vitro Antifungal Activity of Moringa Oleifera Lam Leaf on Some Selected Clinical Fungal Strains. Indian Journal Of Applied Research, 6(8). Hal 548-552.

Karam El-Din, A.-Z. A., Al-Basri, H. M., dan El-Naggar, M. Y. 2012. Critical factors affecting the adherence of Candida albicans to the vaginal epithelium. Journal of Taibah University for Science, 6, :10-18.

Krisnadi, A.D., 2015. Kelor Super Nutrisi. Blora: Pusat Informasi dan Pengembangan Tanaman Kelor Indonesia.

Khomariah dan Ridhawati Sjam. 2012. Kolonilisasi Candida Dalam Rongga Mulut. Majalah Kedokteran. FK UKI, XXVIII: 39-47.

Mukhriani. 2014. Ekstraksi, Pemisahan Senyawa, dan Identifikasi Senyawa Aktif. Jurnal Kesehatan, 7 (2): 361-367.

Naglik, J.R., Richardson, J.P., dan Moyes, D.L. 2014. Candida albicans Pathogenicity and Epithelial Immunity, PLOS Pathogens, 10 (8) : 1-4.

Nuryanti, S., Mustapa, K., dan Sudarmo, I. G. 2016. Uji daya hambat ekstrak buah kelor (Moringa oleifera Lamk) terhadap pertumbuhan jamur Candida albicans. Jurnal Akademika Kimia, 5(4), 178-184.

Nweke, F., Antifungal Activity of Petroluem Ether Extracts of Moringa oleifera Leaves and Stem Bark against Some Plant Pathogenic Fungi, Journal of Natural Sciences Research, 5 (8): 1-5, 2015.

Oluduro, A. O. 2012. “Evaluation of antimicrobial properties and nutritional potentials of Moringa oleifera Lam”. leaf in South-Western Nigeria,” Malaysian Journal of Microbiology. 8(2), 59-67.

Pandey, A., dkk 2012. Moringa oleifera Lam. Sahijan)-A Plant with a Plethora of Diverse Therapeutic Benefits: An Updated Retrospection. Medicinal and Aromatic Plants, 1(1), 1-8.

Patel P, dkk. 2014 Phytochemical Analysis And Antifungal Activity Of Moringa Oleifera. International Journal of Pharmacy and Pharmaceutical Sciences. Vol. 6 (5): 144- 147.

Prince Edwin Das, dkk. 2020. Green Synthesis of Encapsulated Copper Nanoparticles Using a Hydroalcoholic Extract of Moringa oleifera Leaves and Assessment of Their Antioxidant and Antimicrobial Activities. Mdpi, 25. Hal 1-17

Rabiu Sani Shawai, dan Rita Singh. 2016. Phytochemical Screening, Antioxidant And Antimicrobial Activity Of Moringa Oleifera Leaf Extract. International Journal of Innovation Sciences and Research, 05(06). Hal 778-785.

Rusmiati. 2010. Pengaruh Metode Ekstrak Terhadap Aktivitas Antimikroba Ekstrak Metanol Daun Mimba,” Skripsi. Fakultas Ilmu Kesehatan UIN Alauddin Makasar.

Syahruramadhan Muh, Nur Arfa Yanti, Lili Darlian.2016. “Aktivitas Antijamur Ekstrak Daun Kelor (Moringa oleifera Lamck.) Dan Dau Kirinyuh (Chromolaena odorata L.) Terhadap Candida albicans Dan Aspergillus flavus”. J.AMPIBI, 1(2), 7-12.

Toripah SS, Abidjulu J, Wehantouw F. 2014. Aktivitas Antioksidan Dan Kandungan Total Fenolik Ekstrak Daun Kelor (Moringa oleifera Lam). Pharmacon 3(4): 37-43.

Utami, P., dan Puspaningtyas, D.E., 2013. The Miracle of Herbs. Jakarta: AgroMedia Pustaka.

Widowati, I., Efiyati, S., dan Wahyuningtyas, S. 2014. Uji Aktivitas Antibakteri Ekstrak Daun Kelor (moringa oleifera) terhadap Bakteri Pembusuk Ikan Segar (Pseudoonas Aeruginosa). Pelita-Jurnal Penelitian Mahasiswa UNY, 9(02). Hal 146-157